@inproceedings{b61e5873b7194cb88e3737c9838a6ae2,
title = "A Preliminary Comparison of P-Tool Consistency",
abstract = "Many Bioinformatics tools, known as p-tools, have been developed to predict the effect of single nucleotide polymorphisms (SNPs) on gene functionality, in an effort to reduce the need for in-vivo assays. However, the large number of p-tools available and the heterogeneity of their output make their selection and comparison difficult. To study the consistency of predictions across p-tools, here we present two indices and test them on five p-tools whose predictions are based on different types of background information. For this test, SNPs from well-known organism Drosophila melanogaster are considered.",
keywords = "Gene functionality, Missense nonsense mutation, SNP",
author = "Javier Murillo and Flavio Spetale and Elizabeth Tapia and Flavia Krsticevic and Olivier Cailloux and Serge Guillaume and Gustavo Vazquez and Tamara Fernandez and Sebastien Destercke and Sergio Ponce and Pilar Bulacio",
note = "Publisher Copyright: {\textcopyright} 2020, Springer Nature Switzerland AG.; 8th Latin American Conference on Biomedical Engineering and the 42nd National Conference on Biomedical Engineering, CLAIB-CNIB 2019 ; Conference date: 02-10-2019 Through 05-10-2019",
year = "2020",
doi = "10.1007/978-3-030-30648-9_97",
language = "Ingl{\'e}s",
isbn = "9783030306472",
series = "IFMBE Proceedings",
publisher = "Springer",
pages = "731--735",
editor = "{Gonz{\'a}lez D{\'i}az}, {C{\'e}sar A.} and {Chapa Gonz{\'a}lez}, Christian and {Laciar Leber}, Eric and V{\'e}lez, {Hugo A.} and Puente, {Norma P.} and Dora-Luz Flores and Andrade, {Adriano O.} and Galv{\'a}n, {H{\'e}ctor A.} and Fabiola Mart{\'i}nez and Renato Garc{\'i}a and Trujillo, {Citlalli J.} and Mej{\'i}a, {Aldo R.}",
booktitle = "8th Latin American Conference on Biomedical Engineering and 42nd National Conference on Biomedical Engineering - Proceedings of CLAIB-CNIB 2019",
}